The first Druuna story, which appeared in the 80's, begins with a a young woman reading a book about the past where there are green fields and trees. But when we cut to the present we are on a world where the human inhabitants cannot have children and are affected by a plague, the Morbus Gravis, which causes them to mutate horribly. One such human is Shastar, her boyfriend.

Druuna's adventures begin when she goes out to find some drugs for Shastar to help halt the effects of the plague. The adventures take place over several books and eventually over many generations. In them Druuna frequently loses her clothes and has to indulge in all manner of sexual adventures with lovers, bandits, mutants, scientists and the like. In the later books she isn't even Druuna but a clone and then perhaps even an android.

Sometimes the plot is lost along with the clothes but in the first story - "Morbus Gravis" - it is reasonably easy to follow though a little familiar. It Turns out she is on board a space ship which has fled Earth long ago. The space ship is now controlled by a computer which has evolved organically. 

Druuna is also a feistier heroine in this first story. Later as the plot gets more complex when another space ship arrives (with old Serpieri himself on board) the . adventures become more sexually explicit but arguably less dramatically interesting - if you care.

As the series progresses it is not even Druuna we see but variations of her as a clone or robot. The illustration is excellent throughout.

Prior to finding fame as a purveyer of sci-fi hardcore Serpieri was better known for drawing realistic westerns.

Albeit a bit more explicit than Lieutenant Blueberry.